SubtiBank SubtiBank
ywdH [2018-02-13T02:36:10.000Z]
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ywdH [2018-02-13T02:36:10.000Z]

similar to aldehyde dehydrogenase
locus
BSU37960
pI
9.62
mw
50.60 kDa
protein length
457 aa Sequence Blast
gene length
1371 bp Sequence Blast
function
unknown
product
unknown
essential
no
ec
1.2.1.3
synonyms
ipa-58r
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    3,896,290 → 3,897,660

    The protein

    Catalyzed reaction/ biological activity

  • An aldehyde + NAD+ + H2O = an acid + NADH (according to Swiss-Prot)

    • Protein family

  • aldehyde dehydrogenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|EF0AAAF5BAE8E1F54FCA296643F7B9E3CE257B1D|YfmT], [protein|F9CF067A2A8E3B2BACC6A51A0E87E84640349980|AldY], [protein|5B66ADB81AB141982F187B1C5E3A9346AA064DE2|YcbD], [protein|A0BEB92D54799956A4ADE106A1388E5710141069|GabD], [protein|1ADC55F8E265AF86E29743C671CE1EA1BE7EB41E|GbsA], [protein|67A72A0EABCD807C25D8EAC61C251142B45C174E|DhaS], [protein|762718A15E5256261D79DF60F9106AF0CE2D60C6|IolA], [protein|2042F691CB37B1BAFE2CF3906A9F7F47457C3995|PutC], [protein|69838717DC6BB27864D88C282BF5BC7CC558BFD7|RocA], [protein|F3341F205CB939498109D2A54DE842065C488DD5|AldX]

    • Structure

  • [PDB|3RHH] (from from ''Bacillus halodurans'' C-125 complexed with NADP, 28% identity, 62% similarity)

    • Expression and Regulation

    Operons

    genes
    [gene|99F1FAF28FB4817D94E84BD5288FA33124558933|ywdH]
    description
    [Pubmed|9353933]
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    Biological materials

    Mutant

  • MGNA-A564 (ywdH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/564 NBRP B. subtilis, Japan]
  • BKE37960 (Δ[gene|99F1FAF28FB4817D94E84BD5288FA33124558933|ywdH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCGTTTCTCCTTTTTG, downstream forward: _UP4_TAAAAAAGCGCAGATCACCT
  • BKK37960 (Δ[gene|99F1FAF28FB4817D94E84BD5288FA33124558933|ywdH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCGTTTCTCCTTTTTG, downstream forward: _UP4_TAAAAAAGCGCAGATCACCT

    • References

  • 9353933